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  • DeadlineStudy Details:

    1 year (full-time), 2-4 years (part-time)

Course Description

Our MSc in Medical Genetics at Chester is designed to enable you to develop an up-to-date, advanced understanding of human genetic disease.

Why study Medical Genetics at Chester?

During our course, you will study how to apply molecular approaches to the diagnosis and treatment of a range of conditions that have a genetic component. Using specific examples, we will discuss novel approaches to prevention and treatment, as well as the increasing potential of genomics. Throughout the discussions we will consider ethical implications of interventions, and role and nature of genetic counselling. You will also carry out a research project in one of these areas within a research group at the forefront of the field.

The course will be developed to allow you to access most of the course material online – including online text, videos of lectures, and comments and assessments. You will explore skill-oriented areas such as case discussions and ethical discussions in teaching days.

You will join a team of clinical and medical researchers where you will gain the opportunity to gain theoretical, clinical and laboratory-based skills. The research topic will be jointly run by the research team at the Institute of Medicine and the medical staff at one of our partner hospitals.

Features:

  • The modules run in three-day blocks and are therefore suitable for working doctors and healthcare professionals.
  • Assessment is entirely through coursework. This culminates in the dissertation, which is assessed through your production of two publishable scientific articles. Our aim will be to develop these to publication with you if suitable.
  • If biomedical or clinical research is your interest, successful completion of the MSc will allow direct registration onto MD/PhD study, joining our team of researchers at the Institute

Entry Requirements

Applicants must hold an appropriate first degree with a minimum of 2:2 honours (e.g. in Medicine, Biomedical Science, Dietetics, Human Biology) or hold appropriate professional qualifications and be able to demonstrate suitable background knowledge and skills.

Applications are invited from:

  • junior doctors
  • NHS staff
  • international students with appropriate qualifications
  • international doctors or healthcare professionals
  • those with related undergraduate degrees (e.g. Biomedical Science, Dietetics) or equivalent professional qualifications and background experience.

 

Find out more

Fees

https://www1.chester.ac.uk/study/postgraduate/postgraduate-finance/current-postgraduate-fees

Student Destinations

The programme provides specialist training for biomedical scientists, doctors, or healthcare professionals in the field of medical genetics.

It also provides an excellent grounding for those looking to undertake postgraduate research. All candidates would be able to register for a MD or PhD on successful completion of the MSc.

Module Details

 

Programme Structure:

The programme is modular and has six taught modules, each worth 20 credits, plus a 60-credit Research Dissertation.

MD7001: Evidence Based Medicine

This module provides training in the essential skills needed as a researcher or practitioner to use the scientific and medical literature. It will equip you with the skills required to:

  • search the literature
  • critically evaluate research papers
  • write a research review, a systematic review and a meta-analysis
  • determine the appropriate statistical analyses for a given set of clinical data
  • carry out and report statistical analyses.

MD7002: Analysis and Interpretation of Clinical Data

Through a series of practical sessions, this module will develop your understanding of the theories underpinning modern analytical and molecular procedures, and develop your critical appreciation of the uses and limitations of a range of analytical and molecular techniques relevant to clinical and biomedical science. Sessions will cover the following:

  • The value of laboratory tests
  • Limitations of measurements
  • Safety and operational issues – Control of Substances Hazardous to Health (COSHH), Risk Assessment and Standard Operating Procedures (SOPs)
  • Practical sessions – covering aspects of validation
  • Interpretation of laboratory analyses

MD7003: Clinical Medicine

This module utilises the changes that occur during ageing to develop your in-depth knowledge of the pathology of selected organ systems, including the importance of diagnosis and management of human disease. Areas covered include:

  • Concepts – The hallmarks of ageing and inflammageing
  • The life and death of a cell
  • Oxidative stress and disease
  • Ageing – endocrinology, immunology and gene expression
  • Factors affecting lifespan

MD7023: Human Genetic Disease

This module will develop your understanding of disease genetics and the applications of genomic medicine, and will cover the following:

  • The human genome and genetic variation
  • Clinical presentation and course of a range of rare inherited and common diseases
  • Screening, pedigree analysis, genetic counselling
  • Gene regulation: enhancers, promoters, transcription factors, silencers
  • Epigenetics and imprinting
  • Mutational mechanisms: how different types of DNA variants affect gene function or expression to cause disease; correlation of genotype with phenotype

MD7024: Molecular Medicine

This module aims to develop your expertise in molecular approaches applicable to a variety of disease types, and will cover the following:

  • Genotyping and detection of genetic variation
  • Genetic manipulation
  • Animal models – knock-down approaches and gene replacement
  • Stem cells – identification, isolation and manipulation

MD7027: Case Investigations in Molecular Medicine

This module will cover the analysis of cases from different medical specialism, and will examine the following:

  • Oncology
  • Cardiology
  • Endocrinology
  • Neurology
  • Stem-cell-based therapies

MD7100: Research Dissertation

This module is your opportunity to:

  • investigate systematically and in depth a laboratory-based topic of direct relevance to the programme of study and your personal interests
  • draw on and contribute to the development of the growing body of knowledge in the broad clinical/biomedical sciences field
  • present the outcomes of personal research in the form of two publishable scientific articles.

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